Rheumatoid Arthritis, Multiple Sclerosis : Therapy Developed

A

team of researchers at the Institute of Parasitology and Biomedicine of the Supreme Council of Spanish Scientific Research (CSIC), Grenada, has managed to develop in a mouse cell therapy for rheumatoid arthritis and multiple sclerosis, two major autoimmune diseases.

For the two experimental models considered, scientists were able to eliminate the arthritis symptoms and lead to a reversion of the degenerative process.

The arthritis therapy uses a certain type of cells (dendritic cells) which, when injected into animals affected by these disorders, producing regulatory T cells (Treg cells), responsible for the maintenance of immunological tolerance.

Scientific CSIC and the head of the research team, Mario Delgado, explains: "The analysis of cellular mechanisms revealed that these dendritic cells produced in animals treated Treg new cells which act to neutralize the immune cells which, in the case of rheumatoid arthritis, attack components of the joints, or in the case of multiple sclerosis, attack the myelin sheaths of the nerves. "

According to Dr. Delgado, "the results obtained with animals are most promising, but caution is still required as to its possible use on humans because it would then have a" personalized cell therapy involving high costs ".

However, its use could be justified, some degenerative disorders not benefiting from any effective alternative treatment.

Multiple sclerosis is a chronic neurological disease and severe, present everywhere in the world. His high social cost and the fact that it primarily affects young adults make it a priority and urgent issue at both clinical and social.



Related Post :
Rheumatoid Arthritis Is A Serious Illness
Chronic and progressive disease, rheumatoid arthritis affects 300 000 people in France. It concerns mainly women (3 women to 1 man). ...
Arthritis Finally Foiled
"The treatments against rheumatoid arthritis have been dramatic progress over ... "While 30 years ago, a person with rheumatoid arthritis is destined to a ...
Vitamin D Could Reduce Rheumatoid Arthritis Risk
Vitamin D may have beneficial effects on rheumatoid arthritis, according to a study published in the January issue of the journal Arthritis & Rheumatism. ...
New Treatment Of Rheumatoid Arthritis With Anti-Inflammatory Exosomes
Group of orthopedic surgeons Dusseldorf (Germany) has discovered a new class of compounds biological for the treatment of rheumatoid arthritis. ...