New Treatment Of Rheumatoid Arthritis With Anti-Inflammatory Exosomes

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group of orthopedic surgeons Dusseldorf (Germany) has discovered a new class of compounds biological for the treatment of rheumatoid arthritis. These compounds are called "anti-inflammatory exosomes".

The treatment of 66 patients with rheumatoid arthritis proved effective using this technology. Exosomes are particles cellular leukocytes that play an important role in regulation of the immune system.

For Peter Wehling, PhD Medicine Centre in Düsseldorf molecular orthopedics, Germany: "Exosomes Reclaim the immune system recognize endogenous cells as cells endogenous. "

In total, Wehling has dealt with exosomes patients age 66 various affected by acute rheumatoid arthritis. The status of any of these patients had been significantly improved with a medical or surgical treatment treaty. Patients received a single injection of exosomes in articulating the most painful.

"We have seen a rapid improvement and important in two-thirds of patients, "says Dr. Wehling, who monitored the patients during follow-up periods
can be extended over five years. These improvements have lasted on average three to six months before the treatment will have to exosomes be repeated.

"In light of these positive clinical results, treatment of arthritis with exosomes appears feasible, safe and effective in patients with rheumatoid arthritis, particularly those who do not respond well to treatment basic conventional, "explains Dr. Wehling.

In addition, exosomes can also be an option in the treatment of other immune disorders such as multiple sclerosis and allergies.

Experiments on mice with arthritis have already demonstrated the high degree of safety and efficiency particulate endogenous in the treatment of arthritis. Some studies have long been provided by the group of Düsseldorf to better understand the role played by exosomes in health and immune diseases


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